Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12736095 | 1.00 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12736091 | 0.99 | PARP1 (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12736100 | 0.88 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16385957 | 0.87 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15310277 | 0.86 | L3MBTL3 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12736102 | 0.85 | LMNA (0.58) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL16385959 | 0.85 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15310435 | 0.84 | L3MBTL3 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12736127 | 0.84 | L3MBTL3 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12736106 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607362-B1 | Piperidine and piperazine carboxylates as FAAH inhibitors | ASTELLAS PHARMA INC (JP) | 2014-12-31 | — | — | EP | disclosed |