Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19095447 | 0.85 | TSHR (0.36) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL19095446 | 0.85 | TSHR (0.36) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL3879787 | 0.81 | TSHR (0.42) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL7041913 | 0.76 | GLO1 (0.39) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL25547583 | 0.76 | GLO1 (0.39) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL2864246 | 0.73 | GLO1 (0.37) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL1189435 | 0.72 | ALDH1A1 (0.42) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL21061394 | 0.72 | ALDH1A1 (0.37) | GLO1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL30969049 | 0.72 | LMNA (0.36) | GLO1ALDH1A1LMNAHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL3547234 | 0.72 | ADORA1 (0.38) | GLO1ALDH1A1LMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447080-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-09-20 | — | — | US | disclosed |
| US-9447080-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-09-20 | — | — | US | disclosed |
| US-9365554-B2 | Viral polymerase inhibitors | AVIRAGEN THERAPEUTICS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365554-B2 | Viral polymerase inhibitors | AVIRAGEN THERAPEUTICS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-9120775-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2015-09-01 | — | — | US | disclosed |
| US-9120775-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2015-09-01 | — | — | US | disclosed |
| US-20150175592-A1 | Viral Polymerase Inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2015-06-25 | — | — | US | disclosed |
| US-20150175592-A1 | Viral Polymerase Inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2015-06-25 | — | — | US | disclosed |
| US-20150065445-A1 | Viral Polymerase Inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2015-03-05 | — | — | US | disclosed |
| US-20150065445-A1 | Viral Polymerase Inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2015-03-05 | — | — | US | disclosed |
| US-8785478-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-07-22 | — | — | US | disclosed |
| US-8785478-B2 | Viral polymerase inhibitors | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-07-22 | — | — | US | disclosed |
| WO-2013152391-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013152392-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | WO | disclosed |
| US-20130274179-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | US | disclosed |
| US-20130274218-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | US | disclosed |
| US-20130274179-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | US | disclosed |
| US-20130274218-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175592-A1 | Viral Polymerase Inhibitors | POLR2E, POLM, POLR2H | GLO1 1211/4885ALDH1A1 477/4885LMNA 2218/4885 |
| US-20150065445-A1 | Viral Polymerase Inhibitors | POLR2E, POLM, POLR2H | GLO1 1211/4885ALDH1A1 477/4885LMNA 2218/4885 |
| US-20130274218-A1 | VIRAL POLYMERASE INHIBITORS | POLR2E, POLM, POLR2H | GLO1 1211/4885ALDH1A1 477/4885LMNA 2218/4885 |
| US-20130274179-A1 | VIRAL POLYMERASE INHIBITORS | POLR2E, POLM, POLR2H | GLO1 1211/4885ALDH1A1 477/4885LMNA 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.