⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429653 | 0.65 | — | — | |
| SCHEMBL15313188 | 0.63 | — | — | |
| SCHEMBL28480408 | 0.62 | HMGCR (0.35) | — | |
| SCHEMBL717225 | 0.61 | — | — | |
| SCHEMBL6912319 | 0.61 | — | — | |
| SCHEMBL718224 | 0.61 | — | — | |
| SCHEMBL428952 | 0.61 | — | — | |
| SCHEMBL614579 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL2950697 | 0.59 | — | — | |
| SCHEMBL702420 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181283-B2 | Methods of preparing low molecular weight carbosilanes and precursors thereof | GELEST TECHNOLOGIES, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-8987494-B2 | Low molecular weight carbosilanes, precursors thereof, and methods of preparation | GELEST TECHNOLOGIES, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-20150057462-A1 | METHODS OF PREPARING LOW MOLECULAR WEIGHT CARBOSILANES AND PRECURSORS THEREOF | GELEST, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20130274497-A1 | LOW MOLECULAR WEIGHT CARBOSILANES, PRECURSORS THEREOF, AND METHODS OF PREPARATION | GELEST TECHNOLOGIES, INC. (US) | 2013-10-17 | — | — | US | disclosed |