Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897456 | 0.90 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL4895030 | 0.81 | NPC1 (0.47) | P2RX7NPC1RAB9A | |
| SCHEMBL4898824 | 0.81 | NPC1 (0.58) | P2RX7NPC1RAB9A | |
| SCHEMBL4901099 | 0.79 | NPC1 (0.47) | P2RX7NPC1RAB9A | |
| SCHEMBL4901901 | 0.78 | EPHX2 (0.52) | P2RX7NPC1RAB9A | |
| SCHEMBL4896207 | 0.76 | RAB9A (0.55) | P2RX7NPC1RAB9A | |
| SCHEMBL4893825 | 0.74 | RAB9A (0.57) | P2RX7NPC1RAB9A | |
| SCHEMBL4893187 | 0.73 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL18266446 | 0.72 | PNMT (0.50) | P2RX7 | |
| SCHEMBL4900916 | 0.72 | ALDH1A1 (0.55) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557853-B2 | Aryl fluoroethyl ureas acting as alpha 2 adrenergic agents | ALLERGAN, INC. (US) | 2013-10-15 | — | — | US | disclosed |