Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 4/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.70 |
| ▸ | TTR | P02766 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 3/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.53 |
| ▸ | KDM4A | O75164 | 2/20 | 0.53 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314893 | 0.94 | EYA3 (0.70) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL27992957 | 0.89 | EYA3 (0.80) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL11847986 | 0.84 | EYA3 (0.78) | EYA3PTPN1TTRCYP2C9CYP2C19 | |
| SCHEMBL25389924 | 0.83 | EYA3 (0.82) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL28849127 | 0.82 | EYA3 (0.81) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL1287970 | 0.82 | EYA3 (1.00) | EYA3PTPN1TTRCYP2C9CYP2C19 | |
| SCHEMBL6335384 | 0.81 | EYA3 (1.00) | EYA3PTPN1TTRCYP2C9KDM5A | |
| SCHEMBL6338103 | 0.81 | EYA3 (0.71) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL11843232 | 0.81 | EYA3 (0.77) | EYA3PTPN1TTRCYP2C9CYP2C19 | |
| SCHEMBL1287644 | 0.81 | TTR (1.00) | EYA3PTPN1TTRCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895340-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FELIQS CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9624189-B2 | Fluorinated benzofuran derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-20130274325-A1 | Fluorinated Benzofuran Derivatives | FELIQS CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274325-A1 | Fluorinated Benzofuran Derivatives | FABP3, TNNI3, TNNT2 | EYA3 3283/4885PTPN1 4361/4885TTR 1341/4885 |
| US-20170189370-A1 | FLUORINATED BENZOFURAN DERIVATIVES | FABP3, TNNI3, TNNT2 | EYA3 3283/4885PTPN1 4361/4885TTR 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.