Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.65 |
| ▸ | KDM5A | P29375 | 3/20 | 0.54 |
| ▸ | THRA | P10827 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.53 |
| ▸ | KDM4A | O75164 | 2/20 | 0.53 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992957 | 0.88 | EYA3 (0.80) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL9444753 | 0.87 | EYA3 (0.68) | EYA3PTPN1TTRTHRBNR1H4 | |
| SCHEMBL11846804 | 0.86 | EYA3 (0.63) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL11849369 | 0.84 | EYA3 (0.63) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL25389924 | 0.84 | EYA3 (0.82) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL1287970 | 0.83 | EYA3 (1.00) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL4279914 | 0.82 | EYA3 (0.50) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL15314893 | 0.82 | EYA3 (0.70) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL15314949 | 0.81 | EYA3 (0.70) | EYA3PTPN1TTRKDM5ATHRA | |
| SCHEMBL2944813 | 0.81 | PTPN1 (0.69) | EYA3PTPN1TTRKDM5ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831673-A | The preparation method of Amiodarone Hydrochloride intermediate 2 butyl 3 (the diiodo- benzoyl of 4 hydroxyl 3,5) benzofuran | 连云港市金帅医药化工有限公司 | 2017-06-13 | — | — | CN | claimed |
| WO-2023149549-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |
| US-6844358-B2 | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | WYETH (US) | 2005-01-18 | — | — | US | disclosed |
| US-20040102480-A1 | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | WYETH (US) | 2004-05-27 | — | — | US | disclosed |
| US-6509360-B1 | a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia. | WYETH | 2003-01-21 | — | — | US | disclosed |
| EP-1077965-A1 | PHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| US-6166069-A | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| WO-1999058519-A1 | PHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102480-A1 | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | GPR119, INSR, GCKR | EYA3 4109/4885PTPN1 1600/4885TTR 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.