Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518483 | 0.90 | NAAA (0.60) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL2885818 | 0.79 | GAA (0.50) | L3MBTL1ALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL23462146 | 0.77 | DGKA (0.44) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL6535251 | 0.77 | DGKA (0.59) | NAAADGKAHTR2CMAPTPRSS1 | |
| SCHEMBL9061933 | 0.77 | DGKA (0.44) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL15091885 | 0.77 | NAAA (0.53) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL28886791 | 0.76 | DGKA (0.47) | NAAADGKAHTR2CADRA2AADRA1A | |
| SCHEMBL14818311 | 0.75 | DGKA (0.47) | DGKAHTR2CADRA2AADRA1AMAPT | |
| SCHEMBL2724170 | 0.75 | DGKA (0.47) | DGKANPC1DNM1ALDH1A1TSHR | |
| SCHEMBL23451318 | 0.75 | CYP1A2 (0.57) | DGKAHTR2CADRA2AADRA1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028880-B2 | Silica nanoparticle agent conjugates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130274226-A1 | SILICA NANOPARTICLE AGENT CONJUGATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274226-A1 | SILICA NANOPARTICLE AGENT CONJUGATES | TST, NCL, MSN | NAAA 793/4885DGKA 4240/4885HTR2C 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.