Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA11 | O75493 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629408 | 0.85 | CA1 (0.62) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL13896387 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL2629359 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL9740903 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL8246439 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL10995810 | 0.72 | CA1 (0.58) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL16731192 | 0.71 | TP53 (0.46) | SMN1; SMN2MEN1KMT2ATDP1RAB9A | |
| SCHEMBL10878301 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL8779354 | 0.69 | RAB9A (0.59) | SMN1; SMN2CA1CA2CA9CA12 | |
| SCHEMBL11884256 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137367-A | Benazapril and amlodipine besylate for reducing cardiovascular morbidity | NOVARTIS AG (CH) | 2008-03-05 | — | — | CN | claimed |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | SEQUOIA SCIENCES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-8324264-B1 | Inhibitors of bacterial biofilms and related methods | SEQUOIA SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| CN-101137367-A | Benazapril and amlodipine besylate for reducing cardiovascular morbidity | NOVARTIS AG (CH) | 2008-03-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | BLVRB, MMP8, PGLS | SMN1; SMN2 4885/4885CA1 4061/4885CA2 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.