Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633610 | 1.00 | PDE10A (0.52) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL16806284 | 0.85 | PDE10A (0.47) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL72281 | 0.84 | PDE10A (0.45) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL29798822 | 0.81 | KMT2A (0.46) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL15316166 | 0.81 | PDE10A (0.44) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL15316165 | 0.81 | PDE10A (0.48) | PDE10AALDH1A1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL26967850 | 0.77 | P2RX3 (0.41) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL29774210 | 0.76 | MEN1 (0.39) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL28050224 | 0.75 | LDHA (0.43) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL31544276 | 0.75 | PDE10A (0.47) | PDE10AALDH1A1SMN1; SMN2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621027-A | Dyestuffs for bulk dyeing plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| EP-0683212-A1 | New dyes for the bulk dyeing of synthetic materials | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |