Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.35 |
| ▸ | RELA | Q04206 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15317554 | 0.93 | MAPT (0.36) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL15317542 | 0.80 | MAPT (0.33) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL15317559 | 0.79 | RAB9A (0.40) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL15317545 | 0.78 | MAPT (0.34) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL14226686 | 0.78 | RAB9A (0.42) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL12357935 | 0.78 | RAB9A (0.44) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL12357720 | 0.78 | RAB9A (0.47) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL15317561 | 0.78 | MAPT (0.39) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL12357461 | 0.76 | RAB9A (0.45) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL15317558 | 0.75 | PCSK9 (0.38) | RAB9AMAPTL3MBTL1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |