Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29408668 | 0.87 | ALOX15 (0.69) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL186871 | 0.87 | ALOX15 (0.69) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL12914292 | 0.83 | ALOX15 (0.65) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL12765579 | 0.80 | ALOX15 (0.61) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL1720737 | 0.79 | HSD17B10 (0.70) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL4333750 | 0.79 | RAB9A (0.66) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL10315085 | 0.79 | ALOX15 (0.64) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL1531808 | 0.79 | ALOX15 (0.59) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL29355388 | 0.79 | RAB9A (0.66) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 | |
| SCHEMBL12765576 | 0.77 | RAB9A (0.73) | ALOX15KDM4ERAB9AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020196327-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | 株式会社ヤクルト本社 | 2020-10-01 | — | — | WO | disclosed |
| WO-2011028651-A1 | INHIBITORS OF HUMAN 15-LIPOXYGENASE-1 | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-03-10 | — | — | WO | disclosed |