SCHEMBL1720737

SCHEMBL1720737

c1ccc2c(-c3nnc(-c4cc(-c5nnc(-c6cccc7ccccc67)o5)cc(-c5nnc(-c6cccc7ccccc67)o5)c4)o3)cccc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.70
ALDH1A1 P00352 8/20 0.70
KDM4E B2RXH2 7/20 0.70
RAB9A P51151 4/20 0.70
ATM Q13315 2/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2C19 P33261 1/20 0.70
ALOX15 P16050 6/20 0.59
BCHE P06276 1/20 0.54
ACHE P22303 1/20 0.54
TSHR P16473 5/20 0.51
TDP1 Q9NUW8 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ALOX12 P18054 2/20 0.51
HPGD P15428 7/20 0.50
MAPT P10636 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MAPK1 P28482 2/20 0.50
CASP1 P29466 2/20 0.50
CASP7 P55210 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12765576 0.95 RAB9A (0.73) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL12765590 0.92 RAB9A (0.66) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL29408668 0.91 ALOX15 (0.69) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL186871 0.91 ALOX15 (0.69) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL29355388 0.89 RAB9A (0.66) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL4333750 0.89 RAB9A (0.66) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL12914292 0.87 ALOX15 (0.65) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL19932454 0.86 RAB9A (0.67) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL12181731 0.85 RAB9A (0.61) HSD17B10ALDH1A1KDM4ERAB9AATM
SCHEMBL12765579 0.84 ALOX15 (0.61) HSD17B10ALDH1A1KDM4ERAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404363-B2 Organic light emitting device CANON KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-8404363-B2 Organic light emitting device CANON KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-8253325-B2 Organic light-emitting device with microcavity structure and differing semi-transparent layer materials CANON KABUSHIKI KAISHA (JP) 2012-08-28 US disclosed
US-8253325-B2 Organic light-emitting device with microcavity structure and differing semi-transparent layer materials CANON KABUSHIKI KAISHA (JP) 2012-08-28 US disclosed
US-8118633-B2 Color image display panel and method of producing the same, and color image display apparatus CANON KABUSHIKI KAISHA (JP) 2012-02-21 US disclosed
US-8118633-B2 Color image display panel and method of producing the same, and color image display apparatus CANON KABUSHIKI KAISHA (JP) 2012-02-21 US disclosed
EP-1486549-B1 ORGANIC ELECTROLUMINESCENT ELEMENT TOYOTA JIDOSHOKKI KK (JP) 2012-01-11 EP disclosed
US-8004185-B2 Display apparatus CANON KABUSHIKI KAISHA (JP) 2011-08-23 US disclosed
US-8004185-B2 Display apparatus CANON KABUSHIKI KAISHA (JP) 2011-08-23 US disclosed
US-7952269-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2011-05-31 US disclosed
US-20030164678-A1 Vinyl polymer and organic electroluminescent device DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-04 US disclosed
US-20030075533-A1 Material for organic electroluminescent device and its manufacturing method DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-24 US disclosed
US-20030057826-A1 Nitrogen-containing heterocyclic compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-03-27 US disclosed
US-20030044645-A1 Organic EL device and preparation method TDK CORPORATION (JP) 2003-03-06 US disclosed
EP-1285957-A2 Organic electroluminescent device and method of its preparation TDK Corporation (JP) 2003-02-26 EP disclosed
US-6440588-B1 1,4-DIAZEPINE COMPOUND WITH ELECTRON ATTRACTIVE GROUP SELECTED FROM THE GROUP CONSISTING OF CYANO GROUP, AN ACYL GROUP, AND AN ALKOXY GROUP DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-27 US disclosed
US-20020091256-A1 Azepine compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-11 US disclosed
US-6399226-B1 Material for organic electroluminescence device and method for producing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-04 US disclosed
EP-1107331-A2 Material for organic electroluminescence device and process for producing the same Daicel Chemical Industries, Ltd. (JP) 2001-06-13 EP disclosed
EP-1043915-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND METHOD FOR PRODUCING THE SAME Daicel Chemical Industries, Ltd. (JP) 2000-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030057826-A1 Nitrogen-containing heterocyclic compound NOD1, CYC1, NAP1L1 HSD17B10 2852/4885ALDH1A1 1694/4885KDM4E 972/4885
US-20020091256-A1 Azepine compounds AZI2, ARL1, APOL1 HSD17B10 3350/4885ALDH1A1 440/4885KDM4E 1359/4885
US-20030164678-A1 Vinyl polymer and organic electroluminescent device HVCN1, VMP1, ELAVL1 HSD17B10 1483/4885ALDH1A1 648/4885KDM4E 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.