Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531814 | 1.00 | S1PR1 (0.37) | S1PR1PTPN11MEN1KMT2ACYP2C9 | |
| SCHEMBL9189121 | 0.84 | PTPN11 (0.53) | PTPN11P2RY14 | |
| SCHEMBL11219166 | 0.83 | BRS3 (0.43) | PTPN11MEN1KMT2A | |
| SCHEMBL28709974 | 0.82 | PTPN11 (0.51) | PTPN11P2RY14 | |
| SCHEMBL28860337 | 0.82 | SMN1; SMN2 (0.41) | PTPN11CYP2C9P2RY14DGAT1ALDH1A1 | |
| SCHEMBL1531901 | 0.79 | CYP2C9 (0.42) | MEN1KMT2ACYP2C9ALDH1A1LMNA | |
| SCHEMBL1531903 | 0.79 | CYP2C9 (0.42) | MEN1KMT2ACYP2C9ALDH1A1LMNA | |
| SCHEMBL7745539 | 0.77 | PTPN11 (0.48) | PTPN11PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28390205 | 0.76 | PTPN11 (0.47) | PTPN11CYP2C9P2RY14ALDH1A1LMNA | |
| SCHEMBL11047851 | 0.74 | CYP2C9 (0.46) | PTPN11MEN1KMT2ACYP2C9P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2698411-B9 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-2698411-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2698413-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2698412-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2016-10-12 | — | — | EP | disclosed |
| EP-2358845-B1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL INC (US) | 2014-11-12 | — | — | EP | disclosed |
| EP-2303987-B9 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-8828507-B2 | Alignment facilities for optical dyes | TRANSITIONS OPTICAL, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2303987-B1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2014-03-26 | — | — | EP | disclosed |
| EP-2698412-A2 | Mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2014-02-19 | — | — | EP | disclosed |
| EP-2698411-A2 | Mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2014-02-19 | — | — | EP | disclosed |
| US-7910019-B2 | Mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-7910020-B2 | Liquid crystal compositions comprising mesogen containing compounds | TRANSITIONS OPTICAL, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| WO-2010065406-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20100014010-A1 | FORMULATIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20090326186-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090323011-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090323012-A1 | LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPITCAL, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2009158483-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009158488-A1 | LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| US-20090146104-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100014010-A1 | FORMULATIONS COMPRISING MESOGEN CONTAINING COMPOUNDS | MYOC, RARG, MTX2 | S1PR1 3698/4885PTPN11 2886/4885MEN1 84/4885 |
| US-20090326186-A1 | MESOGEN CONTAINING COMPOUNDS | MYOC, BMP2, RARG | S1PR1 4018/4885PTPN11 3827/4885MEN1 117/4885 |
| US-20090323011-A1 | MESOGEN CONTAINING COMPOUNDS | MYOC, BMP2, RARG | S1PR1 4018/4885PTPN11 3827/4885MEN1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.