Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15319114 | 1.00 | L3MBTL1 (0.46) | L3MBTL1NPSR1LTA4HPPARAHDAC3 | |
| SCHEMBL15318910 | 0.89 | L3MBTL1 (0.47) | L3MBTL1NPSR1LTA4HPPARAHDAC3 | |
| SCHEMBL15318912 | 0.89 | L3MBTL1 (0.47) | L3MBTL1NPSR1LTA4HPPARAHDAC3 | |
| SCHEMBL1913579 | 0.86 | L3MBTL1 (0.49) | L3MBTL1NPSR1LTA4HPPARAHDAC3 | |
| SCHEMBL1913578 | 0.86 | L3MBTL1 (0.49) | L3MBTL1NPSR1LTA4HPPARAHDAC3 | |
| SCHEMBL15319103 | 0.84 | ALOX5 (0.41) | L3MBTL1LTA4HALOX5 | |
| SCHEMBL8300754 | 0.82 | L3MBTL1 (0.52) | L3MBTL1NPSR1PPARAHDAC3HDAC1 | |
| SCHEMBL2944484 | 0.80 | L3MBTL1 (0.50) | L3MBTL1NPSR1PPARAHDAC3HDAC1 | |
| SCHEMBL7616466 | 0.78 | L3MBTL1 (0.51) | L3MBTL1NPSR1PPARAHDAC3HDAC1 | |
| SCHEMBL10667221 | 0.78 | L3MBTL1 (0.46) | L3MBTL1NPSR1LTA4HPPARAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834239-A1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | Astrazeneca AB (SE) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150296-A1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | ASTRAZENECA AB (SE) | 2013-10-10 | — | — | WO | disclosed |