SCHEMBL15319182

SCHEMBL15319182

CCc1csc(C(C)S(=O)(=O)O)n1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 20/20 0.43
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20738599 0.73 SLC6A3 (0.36) PTPRBPTPN1
SCHEMBL18793696 0.73 SLC6A3 (0.36) PTPRBPTPN1
SCHEMBL12468687 0.71 KMT2A (0.44) PTPRBPTPN1
SCHEMBL20929927 0.68 CA2 (0.36)
SCHEMBL20529513 0.67 PTPRB (0.32) PTPRBPTPN1
SCHEMBL15319184 0.67 SLC6A3 (0.36) PTPRB
SCHEMBL25952772 0.66 SLC6A3 (0.34) PTPRB
Bromide SCHEMBL28858640 0.64 SLC6A3 (0.38) PTPRB
SCHEMBL22577424 0.63 ALDH1A1 (0.36)
SCHEMBL21899349 0.62 CTPS1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013149362-A1 1-(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS GLAXOSMITHKLINE LLC (US) 2013-10-10 WO disclosed