Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15319184 | 0.89 | SLC6A3 (0.36) | SLC6A3HDAC1HDAC6PTPRBALDH1A1 | |
| SCHEMBL2821735 | 0.75 | SLC6A3 (0.47) | SLC6A3HDAC1HDAC6ALDH1A1 | |
| Acetic Acid SCHEMBL7508639 | 0.73 | SLC6A3 (0.46) | SLC6A3HDAC1HDAC6BAZ2A | |
| SCHEMBL11926805 | 0.73 | SLC6A3 (0.49) | SLC6A3HDAC1HDAC6 | |
| Bromide SCHEMBL4084010 | 0.72 | LOXL2 (0.46) | SLC6A3HDAC1HDAC6BAZ2A | |
| SCHEMBL1398198 | 0.70 | ALDH1A1 (0.40) | SLC6A3ALDH1A1TDP1 | |
| SCHEMBL19362878 | 0.70 | PTPRB (0.54) | PTPRB | |
| SCHEMBL3956722 | 0.70 | LOXL2 (0.47) | SLC6A3HDAC1HDAC6BAZ2A | |
| SCHEMBL29721231 | 0.69 | SLC6A3 (0.38) | SLC6A3HDAC1HDAC6BAZ2A | |
| SCHEMBL29794274 | 0.69 | SLC6A3 (0.39) | SLC6A3HDAC1HDAC6PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160267-B | Ionic liquid type composite medium and method for preparing furfural compounds by adopting ionic liquid type composite medium | 安阳工学院 | 2024-01-16 | — | — | CN | claimed |
| CN-115160267-B | Ionic liquid type composite medium and method for preparing furfural compounds by adopting ionic liquid type composite medium | 安阳工学院 | 2024-01-16 | — | — | CN | disclosed |
| CN-115160267-A | Ionic liquid type composite medium and method for preparing furfural compound by using same | 安阳工学院 | 2022-10-11 | — | — | CN | disclosed |