Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15320625 | 0.73 | ADRA2A (0.44) | — | |
| Hydrochloric Acid SCHEMBL15321393 | 0.72 | ADRA2A (0.43) | — | |
| SCHEMBL15319670 | 0.71 | DRD1 (0.49) | DRD1MAOAHTR2AHTR2CHTR2B | |
| SCHEMBL15319889 | 0.70 | DRD1 (0.46) | DRD1HTR2AHTR2CHTR2B | |
| SCHEMBL16534902 | 0.65 | MAOA (0.42) | DRD1MAOA | |
| SCHEMBL13457936 | 0.63 | ACHE (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL12362687 | 0.63 | ACHE (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL15320519 | 0.62 | ADRA2A (0.46) | — | |
| SCHEMBL15321072 | 0.62 | ADRA2A (0.46) | — | |
| SCHEMBL7621892 | 0.62 | HTR2C (0.35) | MAOAHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834233-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | Orion Corporation (FI) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150173-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ORION CORPORATION (FI) | 2013-10-10 | — | — | WO | disclosed |