Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951394 | 0.88 | BRD4 (0.32) | PARP1 | |
| SCHEMBL1531948 | 0.84 | PDCD1 (0.33) | — | |
| SCHEMBL6464431 | 0.84 | PDCD1 (0.33) | — | |
| SCHEMBL1775470 | 0.81 | PDCD1 (0.33) | — | |
| SCHEMBL4061870 | 0.78 | SLC6A2 (0.32) | — | |
| SCHEMBL4064323 | 0.77 | HDAC4 (0.38) | TSHRCYP1A2CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL14645608 | 0.76 | BRD4 (0.30) | — | |
| SCHEMBL5951511 | 0.74 | PDK2 (0.31) | PDK2 | |
| SCHEMBL4063173 | 0.71 | GABRA1 (0.33) | — | |
| SCHEMBL3353069 | 0.70 | PDK2 (0.33) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579416-B2 | Catalyst system for olefin polymerization | BASELL POLYOLEFINE GMBH (DE) | 2009-08-25 | — | — | US | disclosed |
| US-20070149386-A1 | Catalyst system for olefin polymerization | EQUISTAR CHEMICALS, LP | 2007-06-28 | — | — | US | disclosed |