Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615322 | 0.88 | TDP1 (0.46) | MAPTTDP1ATMALDH1A1ELANE | |
| SCHEMBL394001 | 0.81 | CA1 (0.49) | MAPTTDP1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL29115834 | 0.81 | TAS1R3 (0.47) | MAPTTDP1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL25383439 | 0.79 | RAB9A (0.42) | MAPTTDP1ATMALDH1A1ELANE | |
| SCHEMBL3875454 | 0.79 | TDP1 (0.58) | MAPTTDP1ATMALDH1A1ELANE | |
| SCHEMBL17449655 | 0.79 | ALDH1A1 (0.42) | MAPTTDP1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL4224768 | 0.78 | MAPT (0.51) | MAPTTDP1ALDH1A1ELANERECQL | |
| 4-Vinylphenol SCHEMBL2475223 | 0.78 | MIF (0.46) | TDP1ALDH1A1MIFNPC1RECQL | |
| Hydrochloric Acid SCHEMBL31332428 | 0.77 | TDP1 (0.57) | MAPTTDP1ATMALDH1A1ELANE | |
| SCHEMBL4224773 | 0.77 | CES2 (0.48) | MAPTTDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2833926-A1 | NEUROPHILIC NANOPARTICLES | University of Florida Research Foundation, Inc. (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013151650-A1 | NEUROPHILIC NANOPARTICLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-10-10 | — | — | WO | disclosed |