SCHEMBL15323477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28246592	0.87	HTT (0.55)	L3MBTL1HRH3NPC1RAB9AAKR1C3
	SCHEMBL1017258	0.86	HRH3 (0.51)	HRH3NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL12858537	0.83	ALDH1A1 (0.48)	L3MBTL1HRH3NPC1RAB9ANOS3
	SCHEMBL13634492	0.83	SMN1; SMN2 (0.50)	L3MBTL1HRH3NPC1RAB9ANOS3
	SCHEMBL1014420	0.82	HTT (0.60)	NPC1RAB9ASMN1; SMN2KMT2ATP53
	SCHEMBL13634176	0.82	NOS1 (0.50)	L3MBTL1HRH3NPC1RAB9ANOS3
	SCHEMBL6708339	0.82	NPC1 (0.57)	L3MBTL1HRH3NPC1RAB9ANOS3
	SCHEMBL540760	0.80	HRH3 (0.65)	HRH3NPC1RAB9ANOS3NOS1
	SCHEMBL16741170	0.80	KMT2A (0.59)	HRH3NPC1RAB9ANOS3NOS1
	SCHEMBL13161945	0.79	HRH3 (0.62)	HRH3NPC1RAB9ANOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.