Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL1532355 | 0.77 | KDM4E (0.46) | PPARAPPARGKDM4ESRCTGFBR1 | |
| SCHEMBL27294586 | 0.74 | ACHE (0.41) | METKDM4ESRCTGFBR1 | |
| SCHEMBL21881179 | 0.69 | PPARA (0.68) | PPARAPPARGKEAP1NFE2L2KDM4E | |
| SCHEMBL4715482 | 0.69 | MET (0.53) | METKDM4E | |
| SCHEMBL21881591 | 0.67 | PPARA (0.74) | PPARAPPARGKEAP1NFE2L2KDM4E | |
| SCHEMBL7698955 | 0.65 | PPARA (0.45) | PPARAPPARGKDM4ESRC | |
| SCHEMBL21881505 | 0.64 | PPARA (0.56) | PPARAPPARGKDM4E | |
| SCHEMBL20045399 | 0.64 | KMT2A (0.51) | PPARAPPARG | |
| SCHEMBL20869403 | 0.64 | ALDH1A1 (0.52) | PPARAPPARGMETKDM4ESRC | |
| SCHEMBL11397979 | 0.63 | KMT2A (0.64) | PPARAPPARGKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4662777-B2 | — | — | 2011-03-30 | — | — | JP | claimed |
| JP-2006511519-A | — | — | 2006-04-06 | — | — | JP | claimed |
| EP-1578423-A1 | 2-AMINOCARBONYL-QUINOLINE COMPOUNDS AS PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-09-28 | — | — | EP | claimed |
| WO-2004052366-A1 | 2-AMINOCARBONYL-QUINOLINE COMPOUNDS AS PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-06-24 | — | — | WO | claimed |
| EP-1578423-A1 | 2-AMINOCARBONYL-QUINOLINE COMPOUNDS AS PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004052366-A1 | 2-AMINOCARBONYL-QUINOLINE COMPOUNDS AS PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-06-24 | — | — | WO | disclosed |