Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15323877 | 0.92 | ALDH1A1 (0.40) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL1405394 | 0.88 | LMNA (0.56) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL15323825 | 0.81 | ALDH1A1 (0.37) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL13814117 | 0.80 | ALDH1A1 (0.54) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL19506623 | 0.79 | ALDH1A1 (0.53) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL29931094 | 0.79 | ALDH1A1 (0.62) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL5026886 | 0.79 | PRKCA (0.60) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL15323712 | 0.79 | LMNA (0.37) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL19300632 | 0.79 | ALDH1A1 (0.36) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL24634800 | 0.78 | ALDH1A1 (0.79) | LMNAALDH1A1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |