Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 4/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300632 | 0.85 | ALDH1A1 (0.36) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL15323827 | 0.82 | LDHA (0.31) | LMNAALDH1A1 | |
| SCHEMBL20253283 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL15323710 | 0.79 | LMNA (0.46) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL25582606 | 0.78 | PRKCE (0.58) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL1405394 | 0.78 | LMNA (0.56) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL26224946 | 0.75 | LMNA (0.68) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL13258361 | 0.74 | LMNA (0.45) | LMNAALDH1A1EGLN1KDM6BKDM5C | |
| SCHEMBL587060 | 0.74 | ALDH1A1 (0.38) | LMNAALDH1A1EGLN1KDM6BKDM5C | |
| SCHEMBL5026886 | 0.73 | PRKCA (0.60) | LMNAALDH1A1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |