Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL15323295 | 0.77 | PRKCA (0.31) | PRKCA | |
| Acetic Acid SCHEMBL15323296 | 0.77 | KDM4E (0.32) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Demannose SCHEMBL28547923 | 0.75 | LMNA (0.38) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Acetone SCHEMBL2803680 | 0.75 | MAPT (0.38) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Butyric Acid SCHEMBL15324264 | 0.75 | KDM4E (0.31) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Demannose SCHEMBL15324262 | 0.75 | FFAR3 (0.33) | LMNA | |
| SCHEMBL428467 | 0.75 | MAPT (0.40) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL4603636 | 0.75 | MAPT (0.40) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Demannose SCHEMBL14248786 | 0.74 | LMNA (0.42) | KDM4ELMNA | |
| Acetic Acid SCHEMBL29232673 | 0.73 | KDM4E (0.67) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |