SCHEMBL153251

SCHEMBL153251

CCOC(=O)C1CCCN(C)C1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
SMN1; SMN2 Q16637 2/20 0.56
HTT P42858 1/20 0.55
HPGD P15428 1/20 0.54
KDM4E B2RXH2 3/20 0.53
RAB9A P51151 1/20 0.53
CYP2C19 P33261 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12885924 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
SCHEMBL12310224 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
SCHEMBL12898753 0.89 MAPT (0.56) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
SCHEMBL12898087 0.89 MAPT (0.56) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
SCHEMBL6995632 0.89 MAPT (0.56) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
Hydrochloric Acid SCHEMBL28542420 0.88 MAPT (0.54) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
Hydrochloric Acid SCHEMBL28542417 0.88 MAPT (0.54) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
SCHEMBL12633299 0.86 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2HTTKDM4ECYP2C19
SCHEMBL25700853 0.83 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2HTTHPGDKDM4E
SCHEMBL12881570 0.83 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2HTTKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617779-B1 Low odor environmentally-friendly nano-pigment inkjet ink composition JETBEST CORP (TW) 2014-11-05 EP claimed
US-8710118-B2 Nano-pigment inkjet ink composition that has a low odor and is environmentally-friendly JETBEST CORPORATION (TW) 2014-04-29 US claimed
CN-103242694-A Low-odor environment-friendly nano pigment ink-jet ink composition JETBEST CORP 2013-08-14 CN claimed
US-20130190421-A1 LOW ODOR ENVIRONMENTALLY-FRIENDLY NANO-PIGMENT INKJET INK COMPOSITION JETBEST CORPORATION (TW) 2013-07-25 US claimed
EP-2617779-A1 Low odor environmentally-friendly nano-pigment inkjet ink composition JETBEST Corporation (TW) 2013-07-24 EP claimed
US-20240132270-A1 Systems and Methods of Storing 1,1-Disubstituted Alkene Compositions NIPPON SHOKUBAI CO., LTD. (JP) 2024-04-25 US disclosed
CN-117551088-A Green preparation process of high-purity tipedidine hydrochloride 常州贝迪佳尔生物科技有限公司 2024-02-13 CN disclosed
EP-3351570-B1 MODIFIED AND CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING IT LG CHEMICAL LTD (KR) 2023-10-04 EP disclosed
CN-115232109-A PD-1/PD-L1 small molecule inhibitor and application thereof in medicines 广东东阳光药业有限公司 2022-10-25 CN disclosed
WO-2022168880-A1 SYSTEMS AND METHODS OF STORING 1,1-DISUBSTITUTED ALKENE COMPOSITIONS NIPPON SHOKUBAI CO., LTD. (JP) 2022-08-11 WO disclosed
US-20220153932-A1 PREPOLYMERS OF 1,1-DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER SIRRUS INC (US) 2022-05-19 US disclosed
US-20220112151-A1 COMPOSITIONS OF DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER SIRRUS INC (US) 2022-04-14 US disclosed
US-5206240-A Antiarrhythmia agents MERCK & CO., INC. (US) 1993-04-27 US disclosed
US-5102890-A Anxiolytic agents RHONE-POULENC SANTE (FR) 1992-04-07 US disclosed
CN-1053613-A Nitrogen-containing spiro ring MERCK & CO INC (US) 1991-08-07 CN disclosed
EP-0431943-A2 Nitrogen-containing spirocycles MERCK & CO. INC. (US) 1991-06-12 EP disclosed
EP-0328585-A1 METABOLICALLY ACCEPTABLE POLYISOCYANATE ADHESIVES BIORESEARCH INC. (US) 1989-08-23 EP disclosed
US-4829099-A SURGERY, POLYISOCYANATES, POLYISOTHIOCYANATES BIORESEARCH, INC. (US) 1989-05-09 US disclosed
EP-0274259-A2 New renin-inhibitory oligopeptides, their preparaton and their use Sankyo Company Limited (JP) 1988-07-13 EP disclosed
EP-0239309-A2 Oxadiazoles useful in the treatment of senile dementia MERCK SHARP & DOHME LTD. (GB) 1987-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112151-A1 COMPOSITIONS OF DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER PARG, PARN, LIG1 ALDH1A1 274/4885SMN1; SMN2 2910/4885HTT 2049/4885
US-20220153932-A1 PREPOLYMERS OF 1,1-DICARBONYL SUBSTITUTED-1-ALKENE, METHODS TO MAKE THEM, POLYMERS MADE FROM THEM AND METHODS TO MAKE THE POLYMER PLOD1, COL1A1, PLOD2 ALDH1A1 313/4885SMN1; SMN2 2900/4885HTT 305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.