Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558975 | 0.86 | HSD17B1 (0.53) | MCL1TRPA1HSD17B1HSD17B2APP | |
| SCHEMBL28149290 | 0.86 | APP (0.64) | MCL1TRPA1HSD17B1APPALOX5AP | |
| SCHEMBL2030094 | 0.85 | TLR8 (0.49) | TLR8MCL1HSD17B1HSD17B2APP | |
| SCHEMBL27867853 | 0.85 | DPP4 (0.52) | TLR8MCL1HSD17B1HSD17B2APP | |
| SCHEMBL10604910 | 0.84 | TRPA1 (0.50) | TRPA1ALOX5APFEN1 | |
| SCHEMBL17725805 | 0.81 | APP (0.61) | TLR8MCL1HSD17B1HSD17B2APP | |
| SCHEMBL11037218 | 0.80 | MCL1 (0.64) | TLR8MCL1TRPA1HSD17B1HSD17B2 | |
| SCHEMBL22381413 | 0.80 | TLR8 (0.56) | TLR8MCL1HSD17B1HSD17B2APP | |
| SCHEMBL30158721 | 0.80 | MCL1 (0.64) | TLR8MCL1TRPA1HSD17B1HSD17B2 | |
| SCHEMBL27182940 | 0.79 | ALOX5 (0.52) | ARCYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2653500-B1 | FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION, FLAME RETARDANT FOR POLYCARBONATE RESIN, AND METHOD FOR PRODUCING SAME. | MITSUBISHI ENGINEERING-PLASTICS CORP (JP) | 2017-05-31 | — | — | EP | disclosed |
| EP-2653500-A1 | FLAME-RETARDANT POLYCARBONATE RESIN COMPOSITION, FLAME RETARDANT FOR POLYCARBONATE RESIN, AND METHOD FOR PRODUCING SAME. | Mitsubishi Engineering-Plastics Corporation (JP) | 2013-10-23 | — | — | EP | disclosed |