Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558975 | 0.89 | HSD17B1 (0.53) | APPTRPA1ALOX5ALOX5APFEN1 | |
| SCHEMBL15326993 | 0.86 | TLR8 (0.49) | APPTRPA1ALOX5APFEN1MCL1 | |
| SCHEMBL28150211 | 0.84 | APP (0.53) | APPTRPA1ALOX5MCL1PTPN5 | |
| SCHEMBL27182940 | 0.82 | ALOX5 (0.52) | ALOX5GABRA1GABRB2PPARGPTGS2 | |
| SCHEMBL27183350 | 0.82 | IDO1 (0.48) | TRPA1ALOX5GABRA1GABRB2PPARG | |
| SCHEMBL490516 | 0.81 | APP (0.64) | APPALOX5MIFMAPT | |
| SCHEMBL1292802 | 0.79 | ABL1 (0.50) | TRPA1GABRA1GABRB2PPARGPPARA | |
| Formamide SCHEMBL16969080 | 0.78 | APP (0.46) | APPTRPA1ALOX5MCL1PTPN5 | |
| SCHEMBL11647426 | 0.78 | PTGER1 (0.53) | TRPA1ALOX5APFEN1PTPN5GABRA1 | |
| SCHEMBL9808538 | 0.77 | APP (0.58) | APPALOX5MIFPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121330-A | Personal care compositions with glutathione precursors comprising 4-substituted resorcinols and amino acids | 荷兰联合利华有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-104334525-B | catechol O-methyltransferase activity inhibiting compounds | 奥赖恩公司 | 2017-05-10 | — | — | CN | disclosed |