SCHEMBL15329616

SCHEMBL15329616

CC(C1CC1)n1cc(C=O)c(-c2sccc2Br)n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15331394 0.84 PTGS2 (0.35) PTGS2
SCHEMBL2558027 0.80 RAB9A (0.33) PTGS2
SCHEMBL2560791 0.79 RAB9A (0.34) PTGS2
SCHEMBL15333086 0.76 LMNA (0.38) PTGS2
SCHEMBL15331607 0.75 LMNA (0.39) PTGS2
SCHEMBL15332311 0.75 BTK (0.32) PTGS2
SCHEMBL15329820 0.74 ALDH1A1 (0.33) PTGS2
SCHEMBL2559728 0.73 LMNA (0.42) PTGS2
SCHEMBL15330207 0.73 LMNA (0.41) PTGS2
SCHEMBL15331523 0.73 PTGS2 (0.34) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed