Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560769 | 0.83 | KCNH2 (0.40) | ENPP2CHRNB2CHRNA4MGLLFDPS | |
| SCHEMBL3652437 | 0.82 | CHRNB2 (0.64) | ENPP2ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL2562215 | 0.79 | LPL (0.47) | ENPP2ALDH1A1CHRNB2CHRNA4FDPS | |
| SCHEMBL2562067 | 0.79 | ENPP2 (0.49) | ENPP2ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL2557585 | 0.79 | ENPP2 (0.45) | ENPP2ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL29951590 | 0.76 | KDM4E (0.58) | ENPP2KDM4ETSHRESR1 | |
| SCHEMBL2561427 | 0.76 | ENPP2 (0.42) | ENPP2ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL26995673 | 0.75 | TAAR1 (0.49) | ALDH1A1KDM4ECHRNB2CHRNA4KCNH2 | |
| SCHEMBL1330774 | 0.75 | ENPP2 (0.53) | ENPP2ALDH1A1KDM4EMGLLLMNA | |
| SCHEMBL29951803 | 0.75 | ENPP2 (0.50) | ENPP2ALDH1A1KDM4ECHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |