Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.68 |
| ▸ | MAOB | P27338 | 9/20 | 0.68 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116280 | 0.86 | MAOA (0.65) | MAOAMAOBPDE3BPDE3ATGM2 | |
| SCHEMBL2561538 | 0.86 | MAOA (0.67) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL30588923 | 0.81 | MAOA (0.74) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL2789935 | 0.81 | MAOA (1.00) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL25367285 | 0.81 | MAOA (0.74) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL29906173 | 0.79 | MAOB (0.72) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL4370977 | 0.79 | CES1 (0.73) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL2788548 | 0.79 | MAOB (0.72) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL11213472 | 0.78 | PDE3B (1.00) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL2557384 | 0.78 | MAOA (0.64) | MAOAMAOBPDE3BPDE3ASLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |