Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.72 |
| ▸ | MAOA | P21397 | 8/20 | 0.72 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | TGM2 | P21980 | 5/20 | 0.53 |
| ▸ | CES1 | P23141 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788548 | 1.00 | MAOB (0.72) | MAOBMAOAPDE3BPDE3ASLC6A11 | |
| 5-Fluoroisatin SCHEMBL183575 | 0.85 | MAOB (0.61) | MAOBMAOAPDE3BPDE3ACASP3 | |
| SCHEMBL2789935 | 0.84 | MAOA (1.00) | MAOBMAOAPDE3BPDE3ASLC6A11 | |
| SCHEMBL25367285 | 0.84 | MAOA (0.74) | MAOBMAOAPDE3BPDE3ASLC6A11 | |
| SCHEMBL30588923 | 0.84 | MAOA (0.74) | MAOBMAOAPDE3BPDE3ASLC6A11 | |
| 5-Fluoroisatin SCHEMBL28512324 | 0.83 | MAOB (0.59) | MAOBMAOAPDE3BPDE3ACASP3 | |
| SCHEMBL4370977 | 0.82 | CES1 (0.73) | MAOBMAOAPDE3BPDE3ASLC6A11 | |
| 5-Fluoroisatin SCHEMBL29155951 | 0.81 | MAOB (0.58) | MAOBMAOAPDE3BPDE3ACASP3 | |
| SCHEMBL11213472 | 0.81 | PDE3B (1.00) | MAOBMAOAPDE3BPDE3ASLC6A11 | |
| SCHEMBL15329893 | 0.79 | MAOA (0.68) | MAOBMAOAPDE3BPDE3ASLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112672744-B | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-10-14 | — | — | CN | disclosed |