Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.74 |
| ▸ | MAOB | P27338 | 5/20 | 0.74 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.70 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 5/20 | 0.55 |
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ROS1 | P08922 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30588923 | 1.00 | MAOA (0.74) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL27489766 | 0.89 | MAOA (0.65) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL2789935 | 0.85 | MAOA (1.00) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL29657257 | 0.84 | ROS1 (0.67) | MAOAMAOBPDE3BPDE3ATGM2 | |
| SCHEMBL281743 | 0.84 | ROS1 (0.67) | MAOAMAOBPDE3BPDE3ATGM2 | |
| SCHEMBL4370977 | 0.84 | CES1 (0.73) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL29906173 | 0.84 | MAOB (0.72) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL2788548 | 0.84 | MAOB (0.72) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL2788213 | 0.83 | MAOA (0.66) | MAOAMAOBPDE3BPDE3ASLC6A11 | |
| SCHEMBL11213472 | 0.82 | PDE3B (1.00) | MAOAMAOBPDE3BPDE3ASLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230272401-A1 | COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF | Genetic Intelligence, Inc | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230272401-A1 | COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF | TARDBP, FUS, RBM17 | MAOA 4118/4885MAOB 3900/4885PDE3B 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.