Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15333149 | 0.85 | MAPT (0.44) | ALDH1A1POLBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15331490 | 0.84 | SMN1; SMN2 (0.53) | PDE4BPDE4DABHD16APDE4APDE4C | |
| SCHEMBL2558728 | 0.84 | ALDH1A1 (0.48) | PDE4BPDE4DABHD16AALDH1A1POLB | |
| SCHEMBL15331454 | 0.84 | KMT2A (0.47) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL15329559 | 0.82 | NPBWR1 (0.42) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL2560455 | 0.81 | KMT2A (0.38) | ALDH1A1POLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL15331661 | 0.81 | DHODH (0.42) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL29953708 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL2560438 | 0.79 | RAB9A (0.50) | ABHD16AALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL15332201 | 0.78 | NPBWR1 (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |