Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017686 | 0.78 | CYP1A2 (0.58) | ALDH1A1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27942077 | 0.77 | ALDH1A1 (0.76) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL256096 | 0.75 | MAPT (0.56) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL16961721 | 0.75 | CYP1A2 (0.59) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL4193955 | 0.75 | ALDH1A1 (0.62) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL5621143 | 0.75 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL12529449 | 0.73 | ALDH1A1 (0.69) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL4199341 | 0.73 | ALDH1A1 (0.65) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL16638510 | 0.72 | CYP1A2 (0.47) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 | |
| SCHEMBL26988884 | 0.72 | ALDH1A1 (0.60) | ALDH1A1POLBKMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |