Styrene

Styrene

SCHEMBL1533058

C=Cc1ccccc1.CC(C#N)=CC=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.49
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45
LMNA P02545 6/20 0.44
MAPT P10636 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
CYP3A4 P08684 1/20 0.44
KMT2A Q03164 2/20 0.43
MAOB P27338 1/20 0.41
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
GLA P06280 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.36
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL27396222 0.92 MCL1 (0.50) MCL1ALDH1A1LMNAMAPTSMN1; SMN2
Benzene SCHEMBL28243692 0.92 MCL1 (0.56) MCL1ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL83957 0.92 MCL1 (0.56) MCL1ALDH1A1LMNAMAPTSMN1; SMN2
Acrylonitrile SCHEMBL3269498 0.90 MCL1 (0.49) MCL1ALDH1A1LMNAMAPTSMN1; SMN2
Styrene SCHEMBL27951255 0.88 MCL1 (0.43) MCL1ALDH1A1TSHRLMNAMAPT
Styrene SCHEMBL10588140 0.87 ALDH1A1 (0.45) MCL1ALDH1A1TSHRLMNAMAPT
Styrene SCHEMBL8564811 0.86 LMNA (0.45) MCL1ALDH1A1LMNAMAPTSMN1; SMN2
Styrene SCHEMBL27938281 0.86 MGLL (0.43) MCL1ALDH1A1TSHRLMNAMAPT
Styrene SCHEMBL11721306 0.86 ALDH1A1 (0.44) MCL1ALDH1A1TSHRLMNAMAPT
Acrylamide SCHEMBL9862117 0.85 MCL1 (0.58) MCL1ALDH1A1LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539687-B Rigid polyvinyl chloride sewage discharge pipe and preparation method thereof 日丰新材有限公司 2023-04-07 CN claimed
EP-1940958-B1 FLAME RETARDANT THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2015-01-21 EP claimed
US-7144981-B2 Process for separating volatile components from polymers BAYER AKTIENGESELLSCHAFT (DE) 2006-12-05 US claimed
EP-2670804-B1 NON-HALOGENATED FLAME RETARDANT POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-07-06 EP disclosed
EP-1940958-B1 FLAME RETARDANT THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2015-01-21 EP disclosed
EP-2292693-B1 Polycarbonate compositions with improved molding capability SABIC INNOVATIVE PLASTICS IP (NL) 2014-12-17 EP disclosed
US-8871865-B2 Flame retardant thermoplastic polycarbonate compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-10-28 US disclosed
EP-2049596-B1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2014-04-23 EP disclosed
US-8674007-B2 Flame retardant and scratch resistant thermoplastic polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-03-18 US disclosed
EP-2203517-B1 SCRATCH RESISTANT POLYCARBONATE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2013-07-17 EP disclosed
US-8222350-B2 blends of a polycarbonate, a polycarbonatesiloxane copolymer, impact modifiers comprising acrylonitrile-butadiene-styrene terpolymer and aromatic olefin copolymers, and gel-type matte adjuvants, used to form moldings having impact strength SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-17 US disclosed
EP-1771514-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND METHOD OF USE THEREOF The General Electric Company (US) 2007-04-11 EP disclosed
WO-2007037952-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF GENERAL ELECTRIC COMPANY (US) 2007-04-05 WO disclosed
US-20070072960-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20070072961-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-7144981-B2 Process for separating volatile components from polymers BAYER AKTIENGESELLSCHAFT (DE) 2006-12-05 US disclosed
WO-2006014283-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND METHOD OF USE THEREOF GENERAL ELECTRIC COMPANY (US) 2006-02-09 WO disclosed
US-20060004154-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof CITIBANK, N.A., AS COLLATERAL AGENT 2006-01-05 US disclosed
US-20040255780-A1 Process for separating volatile components from polymers LANXESS DEUTSCHLAND GMBH (DE) 2004-12-23 US disclosed
US-4141934-A MULTISTAGE, THERMOPLASTIC STYRENE COPOLYMER MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed