Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032682 | 0.95 | LMNA (0.49) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| Styrene SCHEMBL3837504 | 0.90 | LMNA (0.38) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| Styrene SCHEMBL1533058 | 0.86 | MCL1 (0.49) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| Styrene SCHEMBL8536415 | 0.85 | ALDH1A1 (0.44) | LMNAMCL1ALDH1A1KDM4EHTT | |
| Styrene SCHEMBL9722971 | 0.84 | CYP3A4 (0.41) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| SCHEMBL10591788 | 0.83 | LMNA (0.46) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| Methacrylic Acid SCHEMBL1030250 | 0.83 | MCL1 (0.54) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| Acrylic Acid Methyl Ester SCHEMBL28604394 | 0.83 | MCL1 (0.48) | LMNAMCL1ALDH1A1KDM4EHPGD | |
| Styrene SCHEMBL28284849 | 0.82 | ALDH1A1 (0.42) | LMNAMCL1ALDH1A1KDM4EHTT | |
| Styrene SCHEMBL465034 | 0.82 | ALDH1A1 (0.44) | LMNAALDH1A1KDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852124-A | Rubber-modified styrenic resin composition | CHI MEI CORPORATION (TW) | 1998-12-22 | — | — | US | disclosed |
| EP-0629498-B1 | Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content | GEN ELECTRIC (US) | 1998-10-07 | — | — | EP | disclosed |
| US-5492966-A | BI-LOBED: ONE RIGID, ONE RUBBERY; RUBBER LOBES EXHIBIT AFFINITY FOR EACH OTHER AND TEND TO AGGLOMERATE DURING COMPOUNDING TO GIVE LARGE RUBBER PARTICLE SIZES WITH REDUCED GLOSS | GENERAL ELECTRIC COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5486407-A | High rubber backing multi-layer ABS system which exhibits improved chemical resistance to HCFC blowing agents | GENERAL ELECTRIC CO. (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0629498-A1 | Multi layered product comprising an ABS layer with a low rubber content and an ABS layer with a high rubber content | GENERAL ELECTRIC COMPANY (US) | 1994-12-21 | — | — | EP | disclosed |
| EP-0564240-A1 | Impact modified resin compositions | GENERAL ELECTRIC COMPANY (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5047470-A | Thermoplastic Blends | GENERAL ELECTRIC COMPANY (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0363814-A2 | Low-temperature impact blends of polycarbonate, graft copolymer and rigid copolymer | GENERAL ELECTRIC COMPANY (US) | 1990-04-18 | — | — | EP | disclosed |
| US-4855357-A | WITH UNSATURATED MONOMERS GRAFTED TO RUBBER POLYMER SUBSTRATES AND RIGID COMPATIBLE ADDITION COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 1989-08-08 | — | — | US | disclosed |