Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.52 |
| ▸ | CCND1 | P24385 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475481 | 1.00 | CDK4 (0.52) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL1603612 | 0.89 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL870959 | 0.85 | ALDH1A1 (0.55) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL10336119 | 0.84 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL8291205 | 0.84 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL12379239 | 0.84 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| Benzene SCHEMBL3155472 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL25435693 | 0.82 | CDK4 (0.52) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL2096099 | 0.82 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL20110943 | 0.82 | KDM4E (0.72) | MEN1KMT2ANPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |