SCHEMBL870959

SCHEMBL870959

CC(=O)Oc1ccccc1C=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
HPGD P15428 2/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
KDM4E B2RXH2 3/20 0.55
HSD17B10 Q99714 2/20 0.55
BLM P54132 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
PTGS2 P35354 2/20 0.55
TSHR P16473 2/20 0.55
ESR1 P03372 1/20 0.55
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
HMGB1 P09429 1/20 0.55
GGT1 P19440 1/20 0.55
PTGS1 P23219 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
PTGDR2 Q9Y5Y4 1/20 0.55
TLR2 O60603 1/20 0.53
ERN1 O75460 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL3155472 0.98 ALDH1A1 (0.58) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
Naphthalene SCHEMBL3150577 0.94 KMT2A (0.52) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
SCHEMBL27416707 0.89 LMNA (0.55) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
SCHEMBL14010529 0.88 ALDH1A1 (0.52) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
SCHEMBL1603612 0.88 MEN1 (0.60) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL3864807 0.86 ERN1 (0.68) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
SCHEMBL6475481 0.85 CDK4 (0.52) ALDH1A1HPGDKDM4EHSD17B10BLM
SCHEMBL5241671 0.85 MAPK1 (0.57) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
SCHEMBL2390071 0.85 ERN1 (0.56) ALDH1A1HPGDHTTSMN1; SMN2KDM4E
SCHEMBL15330637 0.85 CDK4 (0.52) ALDH1A1HPGDKDM4EHSD17B10BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852556-A Composition for forming bottom spin-on carbon coating and bottom spin-on carbon coating 国科天骥(山东)新材料有限责任公司 2024-10-29 CN claimed
US-20230391828-A1 REGULATORS OF CELL DIVISION TECHNISCHE UNIVERSITAT DRESDEN (DE) 2023-12-07 US claimed
CN-117069645-A Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide 兰州大学 2023-11-17 CN claimed
US-11813237-B2 Creatine, its derivatives, compositions and methods of use thereof YU RUEY J (US) 2023-11-14 US claimed
EP-4225780-A2 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2023-08-16 EP claimed
WO-2023134732-A1 PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASES WITH HIGH PENETRATION PRODRUGS OF ASPIRIN AND OTHER NSAIDS TECHFIELDS PHARMA CO., LTD. (CN) 2023-07-20 WO claimed
US-20230218555-A1 CREATINE, ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE THEREOF YU RUEY J (US) 2023-07-13 US claimed
US-11642328-B2 Creatine, its derivatives, compositions and methods of use thereof YU RUEY J (US) 2023-05-09 US claimed
US-20220401398-A1 CREATINE, ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE THEREOF YU RUEY J (US) 2022-12-22 US claimed
WO-2022074072-A2 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2022-04-14 WO claimed
EP-0151593-A1 ENZYME DERIVATIVES. BEECHAM GROUP PLC (GB) 1985-08-21 EP claimed
WO-1985000521-A1 ENZYME DERIVATIVES BEECHAM GROUP P.L.C. (GB) 1985-02-14 WO claimed
US-4483861-A Antihypertensive sulfur-containing compounds SANTEN PHARMACEUTICAL CO., LTD. (JP) 1984-11-20 US claimed
EP-0023559-B1 2-(PERHYDRO-1,4-DIAZINO)-PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1984-09-19 EP claimed
EP-0024282-B1 BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES Dr. Karl Thomae GmbH (DE) 1983-05-18 EP claimed
US-4217445-A SKIN DISORDERS FOTOBIO HOLDING AG (CH) 1980-08-12 US claimed
US-4192868-A ANTIINFLAMMATORY, ANALGESIC CIBA-GEIGY CORPORATION (US) 1980-03-11 US claimed
US-4060617-A Esters of the ophyllinylacetic acid Wulfing, Johann A. (DT) 1977-11-29 US claimed
US-3975532-A ANALGESIC ICI UNITED STATES INC. (US) 1976-08-17 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391828-A1 REGULATORS OF CELL DIVISION PCNA, BOD1L1, MKI67 ALDH1A1 4673/4885HPGD 1918/4885HTT 3879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.