Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GGT1 | P19440 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982103 | 0.91 | NFE2L2 (0.61) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL4982109 | 0.91 | NFE2L2 (0.61) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL12379239 | 0.90 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL8291205 | 0.90 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL1812624 | 0.89 | KMT2A (0.55) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL15330637 | 0.89 | CDK4 (0.52) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL20110943 | 0.89 | KDM4E (0.72) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL2096100 | 0.89 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL6475481 | 0.89 | CDK4 (0.52) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL2096099 | 0.89 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242144-B2 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-08-14 | — | — | US | disclosed |
| US-20110082176-A1 | Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases | RESVERLOGIX CORP. | 2011-04-07 | — | — | US | disclosed |
| US-7846915-B2 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | Resverlogix Corporation (CA) | 2010-12-07 | — | — | US | disclosed |
| US-20060205792-A1 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | HEPALINK (HONG KONG) LIMITED (HK) | 2006-09-14 | — | — | US | disclosed |
| WO-2006045010-A2 | STILBENES AND CHALCONES FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2006-04-27 | — | — | WO | disclosed |
| US-6066757-A | MAY BE INCORPORATED INTO PHOTOCONDUCTING LAYER OF ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AS CHARGE TRANSPORTING MATERIAL | RICOH COMPANY, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| US-5641598-A | HAVING HIGH RESISTANCE TO THERMAL AND MECHANICAL SHOCK | RICOH COMPANY, LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205792-A1 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | APOB, APOL1, HDLBP | MEN1 4636/4885KMT2A 3632/4885NPC1 42/4885 |
| US-20110082176-A1 | Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases | APOB, APOL1, HDLBP | MEN1 4636/4885KMT2A 3632/4885NPC1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.