SCHEMBL6475481

SCHEMBL6475481

CC(=O)Oc1ccccc1C=CC=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 3/20 0.52
CCND1 P24385 3/20 0.52
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
CCNB2 O95067 1/20 0.50
CDK1 P06493 1/20 0.50
CCNB1 P14635 1/20 0.50
CCNB3 Q8WWL7 1/20 0.50
HSP90AA1 P07900 1/20 0.50
KDM4E B2RXH2 3/20 0.49
PTGS2 P35354 3/20 0.49
HSD17B10 Q99714 2/20 0.49
ALDH1A1 P00352 1/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HMGB1 P09429 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330637 1.00 CDK4 (0.52) CDK4CCND1MEN1KMT2ANPC1
SCHEMBL1603612 0.89 MEN1 (0.60) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL870959 0.85 ALDH1A1 (0.55) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL10336119 0.84 MEN1 (0.50) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL8291205 0.84 MEN1 (0.52) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL12379239 0.84 MEN1 (0.52) MEN1KMT2ANPC1RAB9AHSP90AA1
Benzene SCHEMBL3155472 0.83 ALDH1A1 (0.58) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL25435693 0.82 CDK4 (0.52) CDK4CCND1MEN1KMT2ANPC1
SCHEMBL2096099 0.82 MEN1 (0.51) MEN1KMT2ANPC1RAB9AHSP90AA1
SCHEMBL20110943 0.82 KDM4E (0.72) MEN1KMT2ANPC1RAB9AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665713-A1 NEMATICIDAL COMPOUNDS, THEIR COMPOSITION AND USE THEREOF Bhukhanwala, Komal (IN) 2025-12-24 EP disclosed
WO-2024171230-A1 NEMATICIDAL COMPOUNDS, THEIR COMPOSITION AND USE THEREOF BHUKHANWALA KOMAL (IN) 2024-08-22 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
US-6855713-B2 Benzimidazole derivatives, a process for their manufacture and use as a medicine BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-02-15 US disclosed
US-20030130265-A1 Benzimidazole derivatives, a process for their manufacture and use as a medicine BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 US disclosed
WO-2003024451-A1 2-(2-PHENYLETHYL)-BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2003-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130265-A1 Benzimidazole derivatives, a process for their manufacture and use as a medicine TPSAB1, PRSS3, TPSD1 CDK4 402/4885CCND1 230/4885MEN1 2446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.