Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | PMM2 | O15305 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331775 | 0.89 | P2RX7 (0.40) | P2RX7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL15330442 | 0.86 | TDP1 (0.42) | ALDH1A1LMNAHTTMAPK14CDK4 | |
| SCHEMBL2559318 | 0.86 | MAPK14 (0.35) | P2RX7ALDH1A1MAPK14KDM4E | |
| SCHEMBL15331537 | 0.86 | ALDH1A1 (0.37) | P2RX7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2559765 | 0.83 | CYP17A1 (0.37) | MAPK14KMT2A | |
| SCHEMBL15331152 | 0.80 | PKM (0.44) | ALDH1A1LMNAHTTSMN1; SMN2MAPK14 | |
| SCHEMBL15330919 | 0.77 | PKM (0.46) | ALDH1A1LMNAKMT2A | |
| SCHEMBL15331954 | 0.76 | ALDH1A1 (0.46) | P2RX7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL15330318 | 0.75 | LMNA (0.41) | P2RX7ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL15330275 | 0.75 | IDO1 (0.41) | P2RX7ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |