Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955358 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2ACYP1A2POLBALDH1A1 | |
| SCHEMBL2557844 | 0.85 | ERN1 (0.37) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL29956046 | 0.82 | MPO (0.38) | MEN1KMT2AALDH1A1LMNAERN1 | |
| SCHEMBL2559106 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1ERN1GAA | |
| SCHEMBL15331126 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2ACYP1A2POLBALDH1A1 | |
| SCHEMBL2560999 | 0.80 | GRIN2B (0.40) | MEN1KMT2AALDH1A1GRIN2BERN1 | |
| SCHEMBL29956614 | 0.79 | LMNA (0.43) | MEN1KMT2ALMNAGRIN2BHPGD | |
| SCHEMBL2563489 | 0.79 | ERN1 (0.39) | ALDH1A1ERN1MAPT | |
| SCHEMBL2559335 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2ACYP1A2POLBALDH1A1 | |
| SCHEMBL2558468 | 0.77 | GRIN2B (0.43) | KMT2AALDH1A1GRIN2BHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |