Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560999 | 0.89 | GRIN2B (0.40) | ALDH1A1MEN1KMT2AERN1ACKR3 | |
| SCHEMBL29955288 | 0.88 | ALDH1A3 (0.38) | MPOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2557844 | 0.86 | ERN1 (0.37) | MPOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2558468 | 0.83 | GRIN2B (0.43) | ALDH1A1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15330752 | 0.82 | MEN1 (0.42) | LMNAALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL29957679 | 0.81 | NOTUM (0.39) | LMNAALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL29955419 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29956412 | 0.81 | ERN1 (0.46) | LMNAALDH1A1KMT2AERN1MAPT | |
| SCHEMBL29956614 | 0.80 | LMNA (0.43) | LMNAMEN1KMT2AMAPTACKR3 | |
| SCHEMBL2563489 | 0.80 | ERN1 (0.39) | MPOALDH1A1ERN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |