Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352415 | 0.82 | GABRP (0.32) | GABRG2GABRB3GABRA5 | |
| SCHEMBL2232968 | 0.67 | KDM4E (0.31) | KDM4E | |
| SCHEMBL2236516 | 0.66 | SRD5A1 (0.43) | HCAR1GABRG2GABRB3GABRA5MEN1 | |
| SCHEMBL2235135 | 0.66 | NOTUM (0.39) | HCAR1GABRG2GABRB3GABRA5 | |
| SCHEMBL2237635 | 0.66 | NOTUM (0.38) | HCAR1GABRG2GABRB3GABRA5MEN1 | |
| SCHEMBL2237477 | 0.64 | HCAR1 (0.33) | HCAR1 | |
| SCHEMBL2234607 | 0.64 | HCAR1 (0.40) | HCAR1KDM4EMEN1KMT2A | |
| SCHEMBL1346416 | 0.62 | BRPF1 (0.56) | MEN1KMT2ASCN9A | |
| SCHEMBL23050238 | 0.62 | IDH1 (0.41) | HCAR1GABRG2GABRB3GABRA5KDM4E | |
| SCHEMBL7271413 | 0.60 | GABRG2 (0.57) | GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |