SCHEMBL15340448

SCHEMBL15340448

Cc1cc(O)cc(/C=C/c2ccc(OC(=O)c3ccccc3O)cc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.54
HSD17B10 Q99714 2/20 0.54
ALOX15 P16050 2/20 0.54
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 5/20 0.47
MAOB P27338 4/20 0.47
CASP3 P42574 2/20 0.47
SENP8 Q96LD8 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
MAOA P21397 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
PTGS2 P35354 3/20 0.46
NPC1 O15118 1/20 0.45
PTK2B Q14289 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13587599 0.91 HPGD (0.61) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL13142964 0.88 HPGD (0.58) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL15340457 0.87 MAPT (0.53) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL15340449 0.85 HSD17B10 (0.53) HPGDHSD17B10MEN1KMT2AALDH1A1
SCHEMBL13142961 0.85 HPGD (0.61) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL13143046 0.85 HSD17B10 (0.54) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL13142958 0.83 MAOB (0.58) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL13587597 0.83 HPGD (0.54) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL13143057 0.82 HSD17B10 (0.51) HPGDHSD17B10ALOX15MEN1KMT2A
SCHEMBL15339483 0.82 LMNA (0.49) HPGDHSD17B10ALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130281520-A1 Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders GENMEDICA THERAPEUTICS SL (ES) 2013-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281520-A1 Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders HSD17B14, SORD, GPX4 HPGD 45/4885HSD17B10 73/4885ALOX15 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.