Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079060 | 0.71 | HTT (0.40) | LMNAL3MBTL1HPGDALDH1A1CYP2A6 | |
| SCHEMBL16263341 | 0.70 | CYP2A6 (0.41) | LMNAL3MBTL1HPGDALDH1A1CYP2A6 | |
| SCHEMBL17190983 | 0.70 | ALDH1A1 (0.56) | LMNAL3MBTL1HPGDALDH1A1CYP2A6 | |
| SCHEMBL17190976 | 0.70 | L3MBTL1 (0.59) | LMNAL3MBTL1HPGDALDH1A1MAPT | |
| SCHEMBL12500873 | 0.70 | CYP2A6 (0.50) | ALDH1A1CYP2A6MAOAMAOBMAPT | |
| SCHEMBL13167840 | 0.70 | ALDH1A1 (0.56) | LMNAL3MBTL1HPGDALDH1A1CYP2A6 | |
| SCHEMBL25890369 | 0.69 | ACHE (0.50) | LMNA | |
| SCHEMBL788630 | 0.66 | SMN1; SMN2 (0.46) | LMNAL3MBTL1HPGDALDH1A1MAPT | |
| SCHEMBL11886413 | 0.66 | SMN1; SMN2 (0.46) | LMNAL3MBTL1HPGDALDH1A1MAPT | |
| SCHEMBL10192543 | 0.66 | SMN1; SMN2 (0.46) | LMNAL3MBTL1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661426-B1 | PYRAZOL-4-YL CARBOXAMIDE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-27 | — | — | EP | disclosed |
| US-8653003-B2 | Pyrazol-4-yl carboxamide derivatives as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-18 | — | — | US | disclosed |
| US-8653003-B2 | Pyrazol-4-yl carboxamide derivatives as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-18 | — | — | US | disclosed |
| US-20130281505-A1 | PYRAZOL-4-YL CARBOXAMIDE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-10-24 | — | — | US | disclosed |
| US-20130281505-A1 | PYRAZOL-4-YL CARBOXAMIDE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281505-A1 | PYRAZOL-4-YL CARBOXAMIDE DERIVATIVES AS MICROBIOCIDES | C3AR1, CD209, CCR9 | LMNA 3819/4885L3MBTL1 432/4885HPGD 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.