Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16899803 | 1.00 | HSD17B10 (0.57) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL16899818 | 0.95 | MEN1 (0.58) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL16899816 | 0.95 | MEN1 (0.58) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL15340449 | 0.93 | HSD17B10 (0.53) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL15344013 | 0.90 | KDM4E (0.51) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL16899819 | 0.90 | KDM4E (0.51) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL4257188 | 0.90 | KDM4E (0.69) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL4257179 | 0.90 | KDM4E (0.69) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL16899820 | 0.89 | KDM4E (0.56) | HSD17B10PTGS2KDM4EMEN1KMT2A | |
| SCHEMBL15340458 | 0.88 | KDM4E (0.49) | HSD17B10PTGS2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950987-B2 | Aspirin derivatives and uses thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| US-9950987-B2 | Aspirin derivatives and uses thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2018-04-24 | — | — | US | disclosed |
| US-20180072652-A1 | NOVEL ASPIRIN DERIVATIVES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-15 | — | — | US | disclosed |
| US-20180072652-A1 | NOVEL ASPIRIN DERIVATIVES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-15 | — | — | US | disclosed |
| US-9187402-B2 | Aspirin derivatives and uses thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2015-11-17 | — | — | US | disclosed |
| US-9187402-B2 | Aspirin derivatives and uses thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2015-11-17 | — | — | US | disclosed |
| WO-2015104298-A2 | POLYPHENOL CONJUGATES | ANALYTICAL SERVICES (DE) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015104298-A2 | POLYPHENOL CONJUGATES | ANALYTICAL SERVICES (DE) | 2015-07-16 | — | — | WO | disclosed |
| US-8575217-B2 | Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-11-05 | — | — | US | disclosed |
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072652-A1 | NOVEL ASPIRIN DERIVATIVES AND USES THEREOF | PTGS1, HPGDS, PTGES3 | HSD17B10 1611/4885PTGS2 4/4885KDM4E 3277/4885 |
| US-20130281520-A1 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders | HSD17B14, SORD, GPX4 | HSD17B10 73/4885PTGS2 169/4885KDM4E 3003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.