Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344246 | 0.81 | KIF11 (0.36) | KIF11NPC1LMNAPKMHTT | |
| SCHEMBL3824427 | 0.77 | KIF11 (0.43) | KIF11SLC6A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13019882 | 0.77 | ALDH1A1 (0.51) | KIF11SLC6A4ALDH1A1CYP3A4TSHR | |
| SCHEMBL11853799 | 0.74 | SMN1; SMN2 (0.39) | GAALMNASLC6A4SMN1; SMN2MEN1 | |
| SCHEMBL6231813 | 0.74 | ALDH1A1 (0.44) | KIF11GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL15341305 | 0.74 | KIF11 (0.41) | KIF11SLC6A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3789460 | 0.74 | KIF11 (0.41) | KIF11SLC6A4MEN1KMT2AALDH1A1 | |
| SCHEMBL15344307 | 0.72 | KIF11 (0.40) | KIF11SLC6A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3790261 | 0.69 | KIF11 (0.41) | KIF11SLC6A4MEN1KMT2ACYP3A4 | |
| SCHEMBL15341306 | 0.69 | KIF11 (0.41) | KIF11SLC6A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130280912-A1 | SILICON COMPOUND, SILICON-CONTAINING COMPOUND, COMPOSITION FOR FORMING RESIST UNDERLAYER FILM CONTAINING THE SAME AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |