Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483445 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL3640883 | 0.78 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL15344264 | 0.77 | KIF11 (0.38) | ALDH1A1CYP3A4TSHRHSD17B10SLC6A4 | |
| SCHEMBL18883716 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL3241808 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL15341305 | 0.74 | KIF11 (0.41) | SLC6A4KIF11SLC6A2SLC6A3 | |
| SCHEMBL12300317 | 0.73 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL7887616 | 0.72 | ESR1 (0.52) | ALDH1A1CYP3A4HSD17B10HPGDKIF11 | |
| SCHEMBL18355878 | 0.72 | KIF11 (0.40) | SLC6A4KIF11 | |
| SCHEMBL27633809 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | ALDH1A1 391/4885CYP3A4 170/4885TSHR 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.