Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.35 |
| ▸ | LAP3 | P28838 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797577 | 1.00 | MMP2 (0.42) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL19988192 | 0.79 | MMP2 (0.42) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL17109076 | 0.77 | MMP2 (0.41) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL976101 | 0.77 | TGFBR1 (0.42) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL8336668 | 0.76 | CA12 (0.42) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL9797754 | 0.75 | MMP2 (0.39) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL10424417 | 0.75 | MMP1 (0.39) | MMP2CA2MMP1CA12CA1 | |
| SCHEMBL12942521 | 0.73 | MMP1 (0.38) | MMP2CA2MMP1CA12CA1 | |
| Alafosfalin SCHEMBL456724 | 0.73 | DPP4 (0.48) | MMP2CA2MMP1CA12CA1 | |
| Alafosfalin SCHEMBL11032329 | 0.73 | DPP4 (0.48) | MMP2CA2MMP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038158-A2 | METHODS, COMPOSITIONS, SYSTEMS AND APPARATUS FOR MOLECULAR ARRAY FABRICATION | Life Technologies Corporation (US) | 2011-03-31 | — | — | WO | disclosed |
| EP-0176068-B1 | PROCESS FOR THE PREPARATION OF THE STEREOISOMERS OF 1-AMINO-ALKYLPHOSPHONIC OR 1-AMINO-ALKYLPHOSPHINIC ACIDS | Roche Diagnostics GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4859602-A | ENZYMATIC RESOLUTION USING PENICILLIN AMIDASE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0176068-A2 | Process for the preparation of the stereoisomers of 1-amino-alkylphosphonic or 1-amino-alkylphosphinic acids | Roche Diagnostics GmbH (DE) | 1986-04-02 | — | — | EP | disclosed |